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Stimulator of interferon genes (STING), also known as transmembrane protein 173 (TMEM173) and MPYS/MITA/ERIS is a protein that in humans is encoded by the STING1 gene.STING plays an important role in innate immunity. STING induces type I interferon production when cells are infected with intracellular pathogens, such as viruses, mycobacteria and intracellular parasites. Type I interferon, mediated by STING, protects infected cells and nearby cells from local infection by binding to the same cell that secretes it (autocrine signaling) and nearby cells (paracrine signaling.) It thus plays an important role, for instance, in controlling norovirus infection.STING works as both a direct cytosolic DNA sensor (CDS) and an adaptor protein in Type I interferon signaling through different molecular mechanisms. It has been shown to activate downstream transcription factors STAT6 and IRF3 through TBK1, which are responsible for antiviral response and innate immune response against intracellular pathogen.

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  1. Pete

    The Dream of the Blue Turtles (1985)

    Title: The Dream of the Blue Turtles Artist: Sting Genre: Pop-Rock Released: 1985 Tracks: 1 - If You Love Somebody Set Them Free - 2 - Love Is the Seventh Wave - 3 - Russians - 4 - Children's Crusade - 5 - Shadows in the Rain - 6 - We Work the Black Seam - 7 - Consider Me Gone...
  2. Pete

    On This Day June 1, 1985: Sting Releases His Debut Solo Album “The Dream of the Blue Turtles”

    On this day, June 1, 1985, Sting released his debut solo album, “The Dream of the Blue Turtles.” The album reached number 2 on the US Billboard 200 charts and hit number 1 in Italy, the Netherlands, and Australia. It sold over 3 million copies in the US and features the hit song “If You Love...

  3. Quadrophenia (1979)

    Title: Quadrophenia Tagline: A Way of Life Genre: Drama,Music Director: Franc Roddam Cast: Phil Daniels,Leslie Ash,Phil Davis,Mark Wingett,Sting,Ray Winstone,Garry Cooper,Gary Shail,Toyah Willcox,Trevor Laird,Kate Williams,Michael Elphick,Kim Neve,Benjamin Whitrow,Daniel...
    • Pete
    • Thread
    • 80s movies quadrophenia reggae ska sting the mods the who
    • Replies: 1
    • Forum: 80s Movies
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